Hydrochloric Acid → HCID 58413034, compound

Participants

Reaction Steps

To a stirred suspension of 4-[2-(1-tert-Butoxycarbonyl-pyrrolidin-3-yloxy)-4-fluoro-phenylamino]-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester (1.2 g) in MeOH (4.0 ml) was added HCl in dioxane (4N; 4.0 ml) dropwise. The reaction mixture was stirred for 8 h. The solvent was removed under reduced pressure. The residue was purified by chromatography.

Provenance & Evidence