反应详情

A catalytic amount of 10% Pd/C and 13a (20.0 mg, 0.0510 mmol) in a mixture of 2 mL of dichloromethane and 2 mL of methyl alcohol was stirred during 12 h under H2 at atmospheric pressure. The mixture was filtered through celite, washed with additionally methyl alcohol and triturated from ethyl alcohol to afford 14a (16 mg, 0.0404 mmol, 79%) as a white solid. mp: 303° C.;

1. filtrationThe mixture was filtered through celite
2. washwashed with additionally methyl alcohol
3. customtriturated from ethyl alcohol