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HRID240622

反应详情

EQUATION

反应方程式

HRID 240622 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)c1sc2ncnc(Cl)c2c1C
HCID2759834

Methyl 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylate

C9H7ClN2O2S

结构：Nc1ccc(Cl)cc1O[C@H]1CCCN(C(=O)C(F)(F)F)C1
HCID58413042

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1sc2ncnc(Nc3ccc(Cl)cc3O[C@H]3CCCN(C(=O)C(F)(F)F)C3)c2c1C
HCID58413216

未命名化合物

PROCEDURE

实验过程

Prepared analogously to example 65.1. from 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester and (S)-1-(3-(2-amino-5-chlorophenoxy)piperidin-1-yl)-2,2,2-trifluoroethanone. The temperature was 110° C. for 2 h and no purification with chromatography was necessarily.

WORKUP

后处理

  1. customPrepared analogously to example 65.1
  2. customno purification with chromatography