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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 240626Generated: October 31, 2026

Hydrochloric Acid → HCID 58413035, compound

https://huagongshe.com/reaction/240626

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 58413189HCID 58413189—
SolventMethanolHCID 887—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 58413035HCID 58413035—

Reaction Steps

HCl in Dioxane (4M; 4 ml) was added into a solution of (S)-tert-butyl 3-(3-(6-carbamoyl-5-methylthieno[2,3-d]pyrimidin-4-ylamino)pyridin-2-yloxy)piperidine-1-carboxylate (250 mg) in Methanol (8 ml). The reaction was stirred at room temperature for 1.5 h. The solution was purified by chromatography.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08648068B2
Source datasetuspto-grants-2014_02
ORD IDord-f1b5d33a9e8244799d615e91d17c65b4
Source noteuspto-grants-2014_02