Hydrochloric Acid → HCID 58413161, compound

Participants

Reaction Steps

A mixture of 1.4 g (3.14 mmol) 5-methyl-4-{2-[(R)-(tetrahydro-pyran-3-yl)oxy]-pyridin-3-ylamino}-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester, 20 ml methanol, 7 ml THF and 6.29 ml sodium hydroxid solution (1 M) was stirred at room temperature for 48 hours. Then 6.3 ml hydrochloric acid solution (1M) were added followed by addition of water. The mixture was filtered. The solid was washed with water and diisopropylether and dried in an oven (vacuo).

Provenance & Evidence