HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Bis(2-iodoethoxy)ethane → HCID 66822250, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Bis(2-iodoethoxy)ethane | HCID 593436 | — |
| Reactant | 1-(4-(2-(Diethylamino)ethoxy)phenyl)butan-1-one | HCID 66822369 | — |
| Product | HCID 66822250 | HCID 66822250 | — |
Reaction Steps
The title compound was prepared by using a similar procedure as described for the preparation of 21 except that 1,2-bis-(2-iodoethyloxy)ethane was used instead of 2-(diethylamino)ethyl chloride hydrochloride. This produced the crude product which was purified by flash silica gel column chromatography, eluting with 4:1 hexanes/ethyl acetate to give 43 (3.85 g, 52%) as a clear oil: MS (ES+) m/z 407.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08809377B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-6f2225c5f80f4a8bb88d8e82ab96d4e3 |
| Source note | uspto-grants-2014_08 |