HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-1-methylpiperidine → 4-{4-Fluoro-2-[(S)-(tetrahydro-furan-3-yl)oxy]-phenylamino}-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid (1-methyl-piperidin-4-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-1-methylpiperidine | HCID 2737531 | — |
| Reactant | HCID 58413126 | HCID 58413126 | — |
| Product | 4-{4-Fluoro-2-[(S)-(tetrahydro-furan-3-yl)oxy]-phenylamino}-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid (1-methyl-piperidin-4-yl)-amide | HCID 67397519 | — |
Reaction Steps
Prepared analogously to example 1.4 from 4-{4-fluoro-2-[(S)-(tetrahydro-furan-3-yl)oxy]-phenylamino}-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid and 1-methyl-piperidin-4-ylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648068B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-3f68f76cab134e37b7cbf57f36b37b3f |
| Source note | uspto-grants-2014_02 |