HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → 5-(3-Hexyl-1-methyl-1H-indol-2-yl)-5-oxo-pentanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 5-(3-Hexyl-1-methyl-1H-indol-2-yl)-5-oxo-pentanoic acid methyl ester | HCID 66643981 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 5-(3-Hexyl-1-methyl-1H-indol-2-yl)-5-oxo-pentanoic acid | HCID 49800280 | — |
Reaction Steps
To a solution of 5-(3-hexyl-1-methyl-1H-indol-2-yl)-5-oxo-pentanoic acid methyl ester in isopropanol and water was added LiOH and stirred for 3 hours. The reaction was treated with 1M HCL and ethyl acetate. The product was purified by column chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08809382B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-0618f4bd4c834dcdad4b612c7bcb1e72 |
| Source note | uspto-grants-2014_08 |