Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonium Chloride → 2-Undec-1-enyl-1H-indole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonium Chloride | HCID 25517 | — |
| 반응물 | Indole-2-carboxaldehyde | HCID 96389 | — |
| 반응물 | Sodium bis(trimethylsilyl)amide | HCID 2724254 | — |
| 반응물 | Decyltriphenylphosphonium bromide | HCID 3084561 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 2-Undec-1-enyl-1H-indole | HCID 66644163 | — |
반응 단계
To a suspension of decyl-triphenyl-phosphonium bromide in THF was added NaHMDS in THF and the mixture was stirred for 30 minutes. A solution of 1H-indole-2-carbaldehyde was added to the reaction mixture and stirred for 3 hours. The reaction mixture was treated with saturated ammonium chloride and ethyl acetate. The product was purified by column chromatography.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08809382B2 |
| 출처 데이터셋 | uspto-grants-2014_08 |
| ORD ID | ord-ff9858c510734755bbb829e7b36223e9 |
| 출처 메모 | uspto-grants-2014_08 |