HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → 3-(S)-Methyl-pentanedioic acid mono-(2-trimethylsilanyl-ethyl) ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | HCID 86665258 | HCID 86665258 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 3-(S)-Methyl-pentanedioic acid mono-(2-trimethylsilanyl-ethyl) ester | HCID 86665259 | — |
Reaction Steps
To the solution of 3-(S)-Methyl-pentanedioic acid methyl ester 2-trimethylsilanyl-ethyl ester in iso-propanol and water was added lithium hydroxide monohydrate and stirred for two hours at RT. The reaction mixture was treated with saturated ammonium chloride and ethyl acetate. The product was purified by column chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08809382B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-8a7c15a82800408a8c70620c287dc923 |
| Source note | uspto-grants-2014_08 |