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HRID2406661

反应详情

EQUATION

反应方程式

HRID 2406661 的结构方程式

REACTANTS

反应物

4
结构：CCOC(C)=O
HCID8857

Ethyl acetate

C4H8O2

结构：[Cl-].[NH4+]
HCID25517

未命名化合物

结构：O.[Li+].[OH-]
HCID168937

Lithium hydroxide, monohydrate

H3LiO2

结构：COC(=O)C[C@H](C)CC(=O)OCC[Si](C)(C)C
HCID86665258

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@H](CC(=O)O)CC(=O)OCC[Si](C)(C)C
HCID86665259

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：O
溶剂HCID962

Water

H2O

结构：CC(C)O
溶剂HCID3776

Isopropanol

C3H8O

PROCEDURE

实验过程

To the solution of 3-(S)-Methyl-pentanedioic acid methyl ester 2-trimethylsilanyl-ethyl ester in iso-propanol and water was added lithium hydroxide monohydrate and stirred for two hours at RT. The reaction mixture was treated with saturated ammonium chloride and ethyl acetate. The product was purified by column chromatography.

WORKUP

后处理

  1. customThe product was purified by column chromatography