5-Chloro-2-(5-methyl-hex-1-enyl)-1H-indole → 5-chloro-2-(5-methyl-hexyl)-1H-indole

HRID 2406678Notes

Reaction equation

HRID 2406678 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([CH:11]=[CH:12][CH2:13][CH2:14][CH:15]([CH3:17])[CH3:16])=[CH:5]2.[H][H]>C(O)C.[Pd]>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([CH2:11][CH2:12][CH2:13][CH2:14][CH:15]([CH3:17])[CH3:16])=[CH:5]2

Participants

5

Reactant 2

HCID 687513205-Chloro-2-(5-methyl-hex-1-enyl)-1H-indoleHCID 178418361HCID 178418361, compound

Product 1

HCID 687469275-chloro-2-(5-methyl-hexyl)-1H-indole

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

5-Chloro-2-(5-methyl-hex-1-enyl)-1H-indole was dissolved in ethanol and 10% palladium on carbon was added to the solution. The reaction flask was sealed and exposed to hydrogen gas under pressure and was stirred for 5 hours. Then the reaction mixture was filtered through Celite. The solvent was evaporated to give 5-chloro-2-(5-methyl-hexyl)-1H-indole.

Workup

  1. customThe reaction flask was sealed
  2. filtrationThen the reaction mixture was filtered through Celite
  3. customThe solvent was evaporated

Sources & evidence

ORD record
ord-6be766e0044a4a62bf3dd8814c8d9cc0
Source dataset
uspto-grants-2014_08
Patent number
US08809382B2

Reaction notes

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