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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2406824Generated: November 1, 2026

Indole-2-carboxylic acid → HCID 178470238, compound

https://huagongshe.com/reaction/2406824

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndole-2-carboxylic acidHCID 72899—
ReactantEthyl 3-(pyrrolidin-3-ylmethoxy)picolinateHCID 66962066—
ReactantHCID 178525710HCID 178525710—
ProductHCID 178470238HCID 178470238—

Reaction Steps

The title compound was prepared according to the procedure described in Step 3 of EXAMPLE 1 using ethyl 3-(pyrrolidin-3-ylmethoxy)picolinate (EXAMPLE 92, Step 2) and trans-4-(trifluoromethyl)cyclohexanecarboxylic acid instead of (R)-3-(pyrrolidin-2-ylmethoxy)picolinamide dihydrochloride and indole-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08809380B2
Source datasetuspto-grants-2014_08
ORD IDord-ff535d13bf6e4e4e94a81b2f199ea7ea
Source noteuspto-grants-2014_08