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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 240683Generated: October 26, 2026

N-Aminomorpholine → 5-(4-chlorophenyl)-N-morpholino-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamide

https://huagongshe.com/reaction/240683

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-AminomorpholineHCID 20315—
Reactant5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinic acidHCID 66686971—
Product5-(4-chlorophenyl)-N-morpholino-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamideHCID 71294166—

Reaction Steps

The title compound was synthesized in analogy to Example 1 using 5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid (CAN 1018782-82-5) and 4-morpholinamine (CAN 4319-49-7) as starting materials; LC-MS (UV peak area/ESI) 100%, 415.0911 (M−H)−.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08648099B2
Source datasetuspto-grants-2014_02
ORD IDord-1ceaa8e9241142ff963a7a3996aed01c
Source noteuspto-grants-2014_02