Propargyl bromide → HCID 86669373, compound

HRID 2406834Notes

Reaction equation

HRID 2406834 reaction equation
[OH:1][C:2]1[C:10]([CH2:11][CH2:12][CH3:13])=[CH:9][C:5]2[O:6][CH2:7][O:8][C:4]=2[CH:3]=1.C(=O)([O-])[O-].[K+].[K+].[CH2:20](Br)[C:21]#[CH:22]>CC(C)=O.C1(C)C=CC=CC=1>[CH2:22]([O:1][C:2]1[C:10]([CH2:11][CH2:12][CH3:13])=[CH:9][C:5]2[O:6][CH2:7][O:8][C:4]=2[CH:3]=1)[C:21]#[CH:20]

Participants

6

Reactant 3

HCID 7842Propargyl bromideHCID 11430Potassium CarbonateHCID 57217791HCID 57217791, compound

Product 1

HCID 86669373HCID 86669373, compound

Reagents, catalysts & solvents 2

HCID 180AcetoneSolventHCID 1140TolueneSolvent

Procedure

Following the same procedure as in Example 3 a) and b), but using 7.2 g (0.04 moles) of 5-hydroxy-6-propyl-benzo[1.3]dioxole, 5.92 g (0.04 moles) of anhydrous potassium carbonate in 40 ml of acetone were reacted with 5.95 g (0.04 moles) of a solution of propargyl bromide in toluene, (80% w/w).

Sources & evidence

ORD record
ord-1ad6812eb49f4cbca88beacb6daf4497
Source dataset
uspto-grants-2014_08
Patent number
US08809389B2

Reaction notes

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