4-Amino-1lambda~6~,4-thiazinane-1,1-dione → 5-(4-chloro-phenyl)-N-(1,1-dioxido-4-thiomorpholinyl)-6-(2,2,2-trifluoro-ethoxy)-3-pyridinecarboxamide

Participants

Role	Name	HCID	Charge
Reactant	4-Amino-1lambda~6~,4-thiazinane-1,1-dione	HCID 12708263	—
Reactant	5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid	HCID 66686971	—
Product	5-(4-chloro-phenyl)-N-(1,1-dioxido-4-thiomorpholinyl)-6-(2,2,2-trifluoro-ethoxy)-3-pyridinecarboxamide	HCID 71294012	—

Reaction Steps

The title compound was synthesized in analogy to Example 1 using 5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid (CAN 1018782-82-5) and 4-thiomorpholinamine 1,1-dioxide (CAN 26494-76-8) as starting materials; MS (EI) 464.1 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08648099B2
Source dataset	uspto-grants-2014_02
ORD ID	ord-ff76c3ccc7d54a6d90580bdd48967a90
Source note	uspto-grants-2014_02