Pyridine → HCID 25016806, compound

HRID 2406866Notes

Reaction equation

HRID 2406866 reaction equation
[F:1][C:2]1[CH:28]=[CH:27][CH:26]=[C:25]([F:29])[C:3]=1[C:4]([NH:6][C:7]1[CH:8]=[CH:9][C:10]2[C:16]([C:17]3[CH:22]=[CH:21][C:20]([NH2:23])=[CH:19][CH:18]=3)=[CH:15][CH2:14][CH2:13][CH2:12][C:11]=2[CH:24]=1)=[O:5].[C:30](OC(=O)C)(=[O:32])[CH3:31].N1C=CC=CC=1.C(Cl)(=O)C>C(N(CC)CC)C>[F:1][C:2]1[CH:28]=[CH:27][CH:26]=[C:25]([F:29])[C:3]=1[C:4]([NH:6][C:7]1[CH:8]=[CH:9][C:10]2[C:16]([C:17]3[CH:22]=[CH:21][C:20]([NH:23][C:30](=[O:32])[CH3:31])=[CH:19][CH:18]=3)=[CH:15][CH2:14][CH2:13][CH2:12][C:11]=2[CH:24]=1)=[O:5]

Participants

6

Reactant 4

HCID 1049PyridineHCID 6367Acetyl chlorideHCID 7918Acetic AnhydrideHCID 25016805HCID 25016805, compound2×

Product 1

HCID 25016806HCID 25016806, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Compound 9 was prepared by reacting Compound 8 with acetic anhydride in the presence of pyridine or by reacting Compound 8 with acetyl chloride in the presence of triethyl amine.

Sources & evidence

ORD record
ord-faab7adef5564e9496c32d2f08f11209
Source dataset
uspto-grants-2014_08
Patent number
US08809396B2

Reaction notes

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