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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 240688Generated: October 26, 2026

Amoz → 5-(4-chlorophenyl)-N-(5-(morpholinomethyl)-2-oxooxazolidin-3-yl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamide

https://huagongshe.com/reaction/240688

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmozHCID 3016406—
Reactant5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinic acidHCID 66686971—
Product5-(4-chlorophenyl)-N-(5-(morpholinomethyl)-2-oxooxazolidin-3-yl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxamideHCID 71294009—

Reaction Steps

The title compound was synthesized in analogy to Example 1 using 5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid (CAN 1018782-82-5) and 3-amino-5-(4-morpholinylmethyl)-2-oxazolidinone (CAN 43056-63-9) as starting materials; LC-MS (UV peak area/ESI) 97.7%, 515.1292 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08648099B2
Source datasetuspto-grants-2014_02
ORD IDord-777a1fd4f7c54c73908465ffaa5d2247
Source noteuspto-grants-2014_02