3-Chloro-6-(1-methylhydrazinyl)pyridazine → 5-(4-chlorophenyl)-N'-(6-chloropyridazin-3-yl)-N'-methyl-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid hydrazide

Participants

Role	Name	HCID	Charge
Reactant	3-Chloro-6-(1-methylhydrazinyl)pyridazine	HCID 2735815	—
Reactant	5-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid	HCID 66686971	—
Product	5-(4-chlorophenyl)-N'-(6-chloropyridazin-3-yl)-N'-methyl-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid hydrazide	HCID 71509708	—

Reaction Steps

The title compound was synthesized in analogy to Example 1 using 5-(4-chlorophenyl)-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid (CAN 1018782-82-5) and 3-chloro-6-(1-methylhydrazinyl)-pyridazine (CAN 76953-33-8) as starting materials; LC-MS (UV peak area/ESI) 96.8%, 472.0538 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08648099B2
Source dataset	uspto-grants-2014_02
ORD ID	ord-1465b9a1978c4e9e99f714963ac1051e
Source note	uspto-grants-2014_02