Selenium Dioxide → 146535-00-4

HRID 2407071Notes

Reaction equation

HRID 2407071 reaction equation
[CH3:1][C:2]([C:4]1[CH:9]=[C:8]([F:10])[CH:7]=[C:6]([F:11])[CH:5]=1)=[O:3].[Se](=O)=[O:13]>>[F:11][C:6]1[CH:5]=[C:4]([C:2](=[O:3])[CH:1]=[O:13])[CH:9]=[C:8]([F:10])[CH:7]=1

Participants

3

Reactant 2

HCID 24007Selenium DioxideHCID 5185963',5'-Difluoroacetophenone

Product 1

HCID 18784701146535-00-4Yield 85.6%

Procedure

(3,5-Difluorophenyl)(oxo)acetaldehyde (28 g, 84%) was prepared from 3,5-difluoro acetophenone (30.0 g, 192.3 mmol) and selenium dioxide (23.55 g, 214.0 mmol) according to the typical procedure used for Preparation 1.

Workup

  1. customused for Preparation 1

Sources & evidence

ORD record
ord-2cf9a89615424db0adb15b08cd3ec8e5
Source dataset
uspto-grants-2014_08
Patent number
US08809525B2

Reaction notes

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