2-Acetylpyridine → 2-PYRIDINEACETALDEHYDE, ALPHA-OXO-

HRID 2407075Notes

Reaction equation

[Se](=O)=[O:2].[C:4]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][N:8]=1)(=[O:6])[CH3:5]>>[N:8]1[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=1[C:4]([CH:5]=[O:2])=[O:6]

Participants

Reactant 2

HCID 142862-Acetylpyridine

HCID 24007Selenium Dioxide

Product 1

HCID 109535652-PYRIDINEACETALDEHYDE, ALPHA-OXO-Yield 72.2%

Procedure

2-Pyridylglyoxal (8.0 g, crude) was prepared from selenium dioxide (15 g, 135 mmol) and 2-acetyl pyridine (10 g, 82 mmol) according to the typical procedure used for Preparation 1.

Workup

customused for Preparation 1

Sources & evidence

ORD record: ord-9cf0c334079c4b0bb0fb0dc31de40e95
Source dataset: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08809525B2

Reaction notes

Loading…