HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 6-(4,4-Difluoropiperidin-1-yl)-5-phenyl-1,2,4-triazin-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4,4-Difluoropiperidine hydrochloride | HCID 2758351 | — |
| Reactant | 6-Chloro-5-phenyl-1,2,4-triazin-3-amine | HCID 86676115 | — |
| Product | 6-(4,4-Difluoropiperidin-1-yl)-5-phenyl-1,2,4-triazin-3-amine | HCID 67363723 | 14% |
Reaction Steps
6-(4,4-Difluoropiperidin-1-yl)-5-phenyl-1,2,4-triazin-3-amine (39 mg, 14%) was prepared from 6-chloro-5-phenyl-1,2,4-triazin-3-amine (0.20 g, 0.96 mmol), K2CO3 (0.23 g, 1.67 mmol) and 4,4-difluoropiperidine hydrochloride (0.22 g, 1.45 mmol) according to the general procedure of Example 2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08809525B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-adc3551a70454aefbab6123c9cb9e87f |
| Source note | uspto-grants-2014_08 |