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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2407146Generated: October 31, 2026

3-(Trifluoromethyl)piperidine → HCID 53353230, compound

https://huagongshe.com/reaction/2407146

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)piperidineHCID 2760776—
Reactant6-Bromo-5-phenyl-1,2,4-triazin-3-amineHCID 86676114—
ProductHCID 53353230HCID 533532308%

Reaction Steps

5-Phenyl-6-[3-(trifluoromethyl)piperidin-1-yl]-1,2,4-triazin-3-amine (50 mg, 8%) was prepared from 6-bromo-5-phenyl-1,2,4-triazin-3-amine (0.50 g, 1.99 mmol) and 3-(trifluoromethyl)piperidine (0.40 g, 2.58 mmol) according to the general procedure of Example 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08809525B2
Source datasetuspto-grants-2014_08
ORD IDord-45830f49c8d44b259f40c4570e965cf9
Source noteuspto-grants-2014_08