Hydrogen Bromide → 3-(3-piperidinyl)Phenol

HRID 2407219Notes

Reaction equation

Br.C[O:3][C:4]1[CH:5]=[C:6]([CH:10]2[CH2:15][CH2:14][CH2:13][NH:12][CH2:11]2)[CH:7]=[CH:8][CH:9]=1>>[NH:12]1[CH2:13][CH2:14][CH2:15][CH:10]([C:6]2[CH:5]=[C:4]([OH:3])[CH:9]=[CH:8][CH:7]=2)[CH2:11]1

Participants

Reactant 2

HCID 260Hydrogen Bromide

HCID 110742303-(3-Methoxyphenyl)piperidine

Product 1

HCID 129379503-(3-piperidinyl)Phenol

Procedure

HBr can be prepared from 3-(3-methoxyphenyl)piperidine as described in J. Med. Chem., 24 (1981) 1475.

Sources & evidence

ORD record: ord-c519b6eb04b849c8bf1efb62e529a00d
Source dataset: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08809536B2

Reaction notes

Loading…