HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Aminomorpholine → 5-cyclopropyl-N-morpholin-4-yl-6-(2,2,2-trifluoro-ethoxy)-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Aminomorpholine | HCID 20315 | — |
| Reactant | 5-Cyclopropyl-6-(2,2,2-trifluoroethoxy)nicotinic acid | HCID 71294108 | — |
| Product | 5-cyclopropyl-N-morpholin-4-yl-6-(2,2,2-trifluoro-ethoxy)-nicotinamide | HCID 71294400 | — |
Reaction Steps
The title compound was synthesized in analogy to the procedure described in Example 34 c), using 5-cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid (example 34b) and morpholin-4-ylamine as starting materials (CAN 4319-49-7); MS (ESI) 346.4 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648099B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-9aee94d2b5ae4e5c9346a72e99bdb45d |
| Source note | uspto-grants-2014_02 |