Ethylene Glycol → Propylene Glycol

HRID 2407634Notes

Reaction equation

HRID 2407634 reaction equation
[OH:1][CH2:2][CH:3]([CH2:5]O)[OH:4].C(O)CO>CC(O)C>[OH:1][CH2:2][C:3](=[O:4])[CH3:5].[CH2:2]([OH:1])[CH:3]([OH:4])[CH3:5]

Participants

5

Reactant 2

HCID 174Ethylene GlycolHCID 753Glycerol2×

Product 2

HCID 1030Propylene GlycolYield 10%HCID 8299Hydroxyacetone

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

20 wt % glycerol was dehydrated at nitrogen ambient pressure at 220° C. using 80 g of 2-propanol as solvent. 0.01 g/ml of 67% Cu and 33% Cr catalyzed the reaction for 5 h to give glycerol conversion of 37% with 86% selectivity to hydroxyacetone, 10% 1,2-propylene glycol, 4% ethylene glycol and <0.01% to other products.

Workup

  1. customwas dehydrated at nitrogen ambient pressure at 220° C.
  2. customthe reaction for 5 h

Sources & evidence

ORD record
ord-1e644b39214e4584b9a711f54a1d2009
Source dataset
uspto-grants-2014_08
Patent number
US08809593B2

Reaction notes

Loading…