[5-(2-PYRIDINYL)-2-THIENYL]METHANOL → 5-(Pyridin-2-yl)thiophene-2-carbaldehyde

Participants

Reaction Steps

A solution of (5-(pyridin-2-yl)thien-2-yl) methanol (0.100 g) and manganese dioxide (0.136 g) in tetrahydrofuran (3.5 mL) was refluxed overnight. The mixture was cooled to room temperature and the solids were filtered. The filtrate was concentrated and the residue was triturated (hexane:diethyl ether=1:1) to obtain the title compound (8.22 g) having the following physical data.

Provenance & Evidence