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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2407679Generated: October 31, 2026

4-Phenyl-3,4-dihydroisoquinolin-1(2H)-one → HCID 66989293, compound

https://huagongshe.com/reaction/2407679

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Phenyl-3,4-dihydroisoquinolin-1(2H)-oneHCID 12403308—
Reactant6-Chloro-3,4-dihydroisoquinolin-1(2H)-oneHCID 19375637—
ReactantHCID 86659055HCID 86659055—
ProductHCID 66989293HCID 66989293—

Reaction Steps

According to the same procedure described in Example 61, using the compound prepared in Example 65 instead of tert-butyl 4-(bromomethyl)piperidine-1-carboxylate and 4-phenyl-3,4-dihydroisoquinolin-1(2H)-one (prepared according to the reported preparation in Davies, R. V.; et al. J. Chem. Soc. Perkin Trans. 1 1978, 180) instead of 6-chloro-3,4-dihydroisoquinolin-1(2H)-one, the title compound having the following physical data was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08809538B2
Source datasetuspto-grants-2014_08
ORD IDord-2b2eaeb665a0427fa46ccf45c790b652
Source noteuspto-grants-2014_08