HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenyl-3,4-dihydroisoquinolin-1(2H)-one → HCID 66989293, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenyl-3,4-dihydroisoquinolin-1(2H)-one | HCID 12403308 | — |
| Reactant | 6-Chloro-3,4-dihydroisoquinolin-1(2H)-one | HCID 19375637 | — |
| Reactant | HCID 86659055 | HCID 86659055 | — |
| Product | HCID 66989293 | HCID 66989293 | — |
Reaction Steps
According to the same procedure described in Example 61, using the compound prepared in Example 65 instead of tert-butyl 4-(bromomethyl)piperidine-1-carboxylate and 4-phenyl-3,4-dihydroisoquinolin-1(2H)-one (prepared according to the reported preparation in Davies, R. V.; et al. J. Chem. Soc. Perkin Trans. 1 1978, 180) instead of 6-chloro-3,4-dihydroisoquinolin-1(2H)-one, the title compound having the following physical data was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08809538B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-2b2eaeb665a0427fa46ccf45c790b652 |
| Source note | uspto-grants-2014_08 |