反应详情

A solution the compound prepared in Example 250 (0.68 g) in ethanol (11 mL) was treated with hydrazine monohydrate (0.208 mL), followed by 10% palladium-carbon (0.238 g). The mixture was refluxed for 18 hours. After allowing mixture to cool to room temperature, the catalyst was filtered off and washed with methanol. The filtrate was evaporated in vacuo to obtain the title compound (0.510 g) having the following physical data.

1. temperatureThe mixture was refluxed for 18 hours
2. filtrationthe catalyst was filtered off
3. washwashed with methanol
4. customThe filtrate was evaporated in vacuo