反应详情

To a stirred solution of 6-chloro-2-methyl-3-nitropyridine (2.15 g) in ethanol (25 mL) was added sodium ethoxide (4.88 mL) solution at room temperature. The reaction mixture immediately turned dark purple and was refluxed for 2 hours. The reaction mixture was allowed to cool down to room temperature, concentrated in vacuo, and poured into ice. The precipitated solids were collected by filtration to provide the title compound (1.88 g) having the following physical data.

1. temperatureThe reaction mixture immediately turned dark purple and was refluxed for 2 hours
2. concentrationconcentrated in vacuo
3. additionpoured into ice
4. filtrationThe precipitated solids were collected by filtration