HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-amino-4,5-dichloro-6-ethoxypicolinic Acid → 3-amino-4,5-dichloro-6-ethoxy-N-((1-((2-(pyridin-2-yl)thiazol-5-yl)methyl)piperidin-4-yl)methyl)picolinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-amino-4,5-dichloro-6-ethoxypicolinic Acid | HCID 66989333 | — |
| Reactant | (1-((2-(Pyridin-2-yl)thiazol-5-yl)methyl)piperidin-4-yl)methanamine Trihydrochloride | HCID 66989375 | — |
| Product | 3-amino-4,5-dichloro-6-ethoxy-N-((1-((2-(pyridin-2-yl)thiazol-5-yl)methyl)piperidin-4-yl)methyl)picolinamide | HCID 58504157 | — |
Reaction Steps
According to the same procedure described in Example 16, using the compound prepared in Example 431 instead of 4-chloro-3-methoxybenzoic acid and the compound prepared in Example 214 instead of the compound prepared in Example 9, the title compound having the following physical data was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08809538B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-41e99f11091642f688451a2655057fef |
| Source note | uspto-grants-2014_08 |