Perfluoro-2-methyl-3-oxahexanoic acid → HCID 86682209, compound

HRID 2408221Notes

Reaction equation

HRID 2408221 reaction equation
[F:1][C:2]([O:10][C:11]([F:20])([F:19])[C:12]([F:18])([F:17])[C:13]([F:16])([F:15])[F:14])([C:6]([F:9])([F:8])[F:7])[C:3]([OH:5])=[O:4].[Br-].[C:22]([C:26]1[CH:31]=[CH:30][C:29]([S+:32]([C:39]2[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=2)[C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)=[CH:28][CH:27]=1)([CH3:25])([CH3:24])[CH3:23]>>[F:1][C:2]([O:10][C:11]([F:19])([F:20])[C:12]([F:18])([F:17])[C:13]([F:14])([F:15])[F:16])([C:6]([F:9])([F:8])[F:7])[C:3]([O-:5])=[O:4].[C:22]([C:26]1[CH:31]=[CH:30][C:29]([S+:32]([C:39]2[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=2)[C:33]2[CH:34]=[CH:35][CH:36]=[CH:37][CH:38]=2)=[CH:28][CH:27]=1)([CH3:25])([CH3:23])[CH3:24]

Participants

3

Reactant 2

HCID 114481Perfluoro-2-methyl-3-oxahexanoic acidHCID 22625536(4-tert-Butylphenyl)(diphenyl)sulfanium bromide

Product 1

HCID 86682209HCID 86682209, compoundYield 37%

Procedure

Synthesis was carried out as in Synthesis Example 1 aside from using 13.2 g (0.04 mol) of 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propionic acid and an amount (0.06 mol) of 4-tert-butylphenyldiphenylsulfonium bromide aqueous solution. There was obtained 9.5 g of white crystals (yield 37%). The compound thus obtained was analyzed by spectroscopy.

Workup

  1. customSynthesis
  2. customwas carried out as in Synthesis Example 1 aside

Sources & evidence

ORD record
ord-a1af19734bc943158aed61846e49df35
Source dataset
uspto-grants-2014_08
Patent number
US08815492B2

Reaction notes

Loading…