Hexachlorocyclotriphosphazene → HCID 23659263, compound

HRID 2408283Notes

Reaction equation

HRID 2408283 reaction equation
[Na].[OH:2][C:3]1[CH:10]=[CH:9][C:6]([CH:7]=[O:8])=[CH:5][CH:4]=1.[Cl:11][P:12]1(Cl)[N:17]=[P:16](Cl)(Cl)[N:15]=[P:14](Cl)(Cl)[N:13]=1>C1COCC1>[CH:7]([C:6]1[CH:9]=[CH:10][C:3]([O:2][P:16]2([O:2][C:3]3[CH:10]=[CH:9][C:6]([CH:7]=[O:8])=[CH:5][CH:4]=3)[N:17]=[P:12]([O:2][C:3]3[CH:10]=[CH:9][C:6]([CH:7]=[O:8])=[CH:5][CH:4]=3)([Cl:11])[N:13]=[P:14]([O:2][C:3]3[CH:10]=[CH:9][C:6]([CH:7]=[O:8])=[CH:5][CH:4]=3)([O:2][C:3]3[CH:10]=[CH:9][C:6]([CH:7]=[O:8])=[CH:5][CH:4]=3)[N:15]=2)=[CH:4][CH:5]=1)=[O:8]

Participants

4

Reactant 2

HCID 220225HexachlorocyclotriphosphazeneHCID 86630763HCID 86630763, compound

Product 1

HCID 23659263HCID 23659263, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

2591 mg of 4-hydroxybenzaldehyde sodium salt (18 mmol) are added at 0° C. and under an inert atmosphere to a solution containing 1.2 g of hexachlorocyclotriphosphazene (3.45 mmol) in THF (300 mL). The reaction medium is stirred for 12 hours while the temperature is allowed to gradually return to room temperature. The crude reaction product is evaporated to dryness then purified by “flash” chromatography on a silica column. The product is isolated in the form of a translucent oil with a yield of 70%.

Workup

  1. customto gradually return to room temperature
  2. customThe crude reaction product
  3. customis evaporated to dryness
  4. customthen purified by “flash” chromatography on a silica column
  5. customThe product is isolated in the form of a translucent oil with a yield of 70%

Sources & evidence

ORD record
ord-95525d9d72e640fe815a2dfba0c57c43
Source dataset
uspto-grants-2014_08
Patent number
US08815834B2

Reaction notes

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