HRID2408507

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC1(C)CC=C(c2cc(C3(C#N)CCCCC3)ccc2N)CC1

HCID58993717

未命名化合物

结构：C[Si](C)(C)CCOCn1cc(C#N)nc1C(=O)[O-].[K+]

HCID67188357

未命名化合物

PRODUCTS

生成物

结构：CC1(C)CC=C(c2cc(C3(C#N)CCCCC3)ccc2NC(=O)c2nc(C#N)cn2COCC[Si](C)(C)C)CC1

HCID58993758

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 1-[4-amino-3-(4,4-dimethyl-cyclohex-1-enyl)-phenyl]-cyclohexanecarbonitrile (as prepared in the previous step) and 4-cyano-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole-2-carboxylate potassium salt (as prepared in Example 1, step (d)) according to the procedure of Example 1, step (f). Mass spectrum (ESI, m/z): Calcd. for C32H43N5O2Si, 558.3 (M+H), found 557.8.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-46c5896c01124a3ebcc922449833fcf9
来源数据集: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08815867B2
来源说明: uspto-grants-2014_08

反应 SMILES

[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2([C:14]#[N:15])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]2)=[CH:4][C:3]=1[C:16]1[CH2:21][CH2:20][C:19]([CH3:23])([CH3:22])[CH2:18][CH:17]=1.[K+].[C:25]([C:27]1[N:28]=[C:29]([C:40]([O-])=[O:41])[N:30]([CH2:32][O:33][CH2:34][CH2:35][Si:36]([CH3:39])([CH3:38])[CH3:37])[CH:31]=1)#[N:26]>>[C:14]([C:8]1([C:5]2[CH:6]=[CH:7][C:2]([NH:1][C:40]([C:29]3[N:30]([CH2:32][O:33][CH2:34][CH2:35][Si:36]([CH3:39])([CH3:38])[CH3:37])[CH:31]=[C:27]([C:25]#[N:26])[N:28]=3)=[O:41])=[C:3]([C:16]3[CH2:21][CH2:20][C:19]([CH3:23])([CH3:22])[CH2:18][CH:17]=3)[CH:4]=2)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]1)#[N:15]