N-bromobutanimide → HCID 58993735, compound

HRID 2408514Notes

Reaction equation

HRID 2408514 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:13][CH2:12][C:11](=[O:14])[CH2:10][CH2:9]2)=[CH:4][CH:3]=1.C1C(=O)N([Br:22])C(=O)C1>C(Cl)Cl>[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]2[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]2)=[CH:6][C:7]=1[Br:22]

Participants

4

Reactant 2

HCID 67184N-bromobutanimideHCID 233718944-(4-Aminophenyl)cyclohexan-1-one

Product 1

HCID 58993735HCID 58993735, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound was prepared from 4-(4-amino-phenyl)-cyclohexanone (as prepared in the previous step) by bromination with NBS according to the procedure in Example 4, step (b), replacing CH3CN with CH2Cl2. Mass spectrum (ESI, m/z): Calcd. for C12H14NOBr, 268.0/270.0 (M+H), found 268.3/270.2.

Sources & evidence

ORD record
ord-614b6c5c8337435f888047575650cc11
Source dataset
uspto-grants-2014_08
Patent number
US08815867B2

Reaction notes

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