3,4-Difluorobenzonitrile → HCID 74221583, compound

Participants

Reaction Steps

The methyl ester of the title compound is prepared from {(S)-6-[(R)-7-fluoro-4-hydroxy-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester and 3,4-difluoro-benzonitrile following a procedure analogous to that described for Intermediate 12. The title compound is obtained after saponification of the methyl ester as described for Example 1. LC (method 2): tR=1.11 min; Mass spectrum (ESI+): m/z=464 [M+H]+.

Provenance & Evidence