Pargyline → Dopamine

HRID 2408879Notes

Reaction equation

C[N:2](CC1C=CC=CC=1)[CH2:3][C:4]#C.O=[C:14]1O[C@H:19]([C@H:21]([CH2:23][OH:24])[OH:22])[C:17]([O-])=[C:15]1O.[Na+]>>[NH2:2][CH2:3][CH2:4][C:17]1[CH:15]=[CH:14][C:23]([OH:24])=[C:21]([OH:22])[CH:19]=1

Participants

Reactant 2

HCID 4688Pargyline

HCID 23667548Sodium Ascorbate

Product 1

HCID 681Dopamine

Procedure

The uptake reaction mixture was suspended in a final volume of 200 μl containing pargyline (final concentration of 10 μM) and sodium ascorbate (final concentration of 0.2 mg/ml) in each well of 96-well-round-bottom-plate.

Workup

customThe uptake reaction mixture

Sources & evidence

ORD record: ord-506235dc5f074e249183afcfa4fba9bc
Source dataset: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08815871B2

Reaction notes

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