HuagongsheHuagongshe Chemistry Print Report · For research reference only
54639-78-0 → HCID 57497052, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 54639-78-0 | HCID 12530968 | — |
| Reactant | (S)-2-amino-6-(5-amino-2-fluoro-phenyl)-3,5,5,6-tetramethyl-5,6-dihydro-3H-pyrimidin-4-one | HCID 57497157 | — |
| Reactant | HCID 178419135 | HCID 178419135 | — |
| Product | HCID 57497052 | HCID 57497052 | — |
Reaction Steps
The reductive amination of (S)-2-amino-6-(5-amino-2-fluoro-phenyl)-3,5,5,6-tetramethyl-5,6-dihydro-3H-pyrimidin-4-one (intermediate J) and rac-2-hydroxy-4,4-dimethyl-cyclopentanone using decaborane yielded a mixture of epimers of the title compound as white solid. MS (ESI): m/z=391.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08815881B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-97832c953c114ecca9c455463fe470e9 |
| Source note | uspto-grants-2014_08 |