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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2409275Generated: November 2, 2026

4-(4-Fluoro-phenyl)-piperidine hydrochloride → HCID 53377694, compound

https://huagongshe.com/reaction/2409275

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Fluoro-phenyl)-piperidine hydrochlorideHCID 21898168—
ReactantHCID 71178961HCID 71178961—
ProductHCID 53377694HCID 5337769414.9%

Reaction Steps

Using ethyl 3-(N-cyclopropylsulfamoyl)-7-(4-fluoro-2-methylphenylamino)-pyrazolo[1,5-a]pyrimidine-6-carboxylate (0.496 g, 1.145 mmol) obtained in step 1 and 4-(4-fluorophenyl)piperidine hydrochloride (0.072 g, 0.335 mmol) instead of 4-phenylpiperidine, and in the same manner as in Example 1 step 4, the title compound (0.0283 g, 3%) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08815874B2
Source datasetuspto-grants-2014_08
ORD IDord-7ed72e8ec4f249748b1c7bc59e905626
Source noteuspto-grants-2014_08