HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 70348174, compound → HCID 68106252, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 70348174 | HCID 70348174 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 68106252 | HCID 68106252 | 99.2% |
Reaction Steps
Benzyl[(3-hydroxypyrrolidin-1-yl)sulfonyl]carbamate (2.55 g) was added to MeOH, and subsequently, 10% palladium carbon (657 mg, 55% wet) was added thereto, followed by stirring at a normal temperature/a normal pressure for about 3 hours under a hydrogen atmosphere. The catalyst was collected by filtration through Celite, and the filtrate was concentrated under reduced pressure to obtain 3-hydroxypyrrolidin-1-sulfonamide (1.4 g) as a colorless oily substance.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08815920B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-c205ccf1031f456ebf24e3a6db335a27 |
| Source note | uspto-grants-2014_08 |