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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 241009Generated: November 1, 2026

2-Hydroxy-2-methylpropanimidamide hydrochloride → 2-(4-Chloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazolin-2-yl)propan-2-ol

https://huagongshe.com/reaction/241009

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Hydroxy-2-methylpropanimidamide hydrochlorideHCID 42614284—
ReactantHCID 178425726HCID 178425726—
Product2-(4-Chloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazolin-2-yl)propan-2-olHCID 86647816—

Reaction Steps

Synthesized according to the method of reagent preparation 8 using 2-hydroxy-5,5-dimethylcyclohex-1-enecarboxylate and 2-hydroxy-2-methylpropanimidamide hydrochloride in step 2. MS (ES) for C13H19ClN2: 255 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08648066B2
Source datasetuspto-grants-2014_02
ORD IDord-a01ee170ac154412b6f505c1205c9d38
Source noteuspto-grants-2014_02