HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzaldehyde → HCID 86707785, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzaldehyde | HCID 7726 | — |
| Reactant | ethyl 2-bromo-5-((4-chlorophenyl)(hydroxy)methyl)-1-isopropyl-1H-imidazole-4-carboxylate | HCID 86707749 | — |
| Product | HCID 86707785 | HCID 86707785 | — |
Reaction Steps
The title compound was obtained in analogy to the procedure described for intermediate B but using 4-chlorobenzaldehyde and the product from step 256.5. After completion, the reaction mixture was quenched with a 1M NH4Cl solution and extracted with EtOAc. The organic layer was dried (Na2SO4), filtered and concentrated. The residue was purified by flas chromatography (heptane/EtOAc, 80:20→20:80) to give the title compound. tR: 1.08 min (LC-MS 2); ESI-MS: 431.1/433.0 [M+H]+ (LC-MS 2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08815926B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-e4e06ebd799c4d9aa45c41199c3b3d1d |
| Source note | uspto-grants-2014_08 |