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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2410145Generated: October 31, 2026

2,6-Dimethyl-4-aminopyrimidine → HCID 86707788, compound

https://huagongshe.com/reaction/2410145

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-Dimethyl-4-aminopyrimidineHCID 68039—
Reactantethyl 2-bromo-5-((4-chlorophenyl)(hydroxy)methyl)-1-isopropyl-1H-imidazole-4-carboxylateHCID 86707749—
ProductHCID 86707788HCID 86707788—

Reaction Steps

The title compound was prepared in analogy to the procedure described for step E2 but using intermediate B and 4-amino-2,6-dimethylpyrimidine. After completion, the reaction mixture was extracted with 1M HCl and washed with a saturated NaHCO3 solution. The organic was dried (Na2SO4), filtered and concentrated. The product was used without further purification. tR: 0.82 min (LC-MS 2); ESI-MS: 506.0/508.1 [M+H]+ (LC-MS 2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08815926B2
Source datasetuspto-grants-2014_08
ORD IDord-362cb062e08647549b9864bae4930f49
Source noteuspto-grants-2014_08