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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2410339Generated: October 25, 2026

Methyl 2,2-dimethyl-3-oxopropanoate → HCID 69319055, compound

https://huagongshe.com/reaction/2410339

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2,2-dimethyl-3-oxopropanoateHCID 11137194—
ReactantMethyl 1-formylcyclobutane-1-carboxylateHCID 15656335—
Reactant4-Isobutoxy-3-(piperidin-4-ylmethoxy)-1,2-benzisoxazoleHCID 69316977—
ProductHCID 69319055HCID 69319055—

Reaction Steps

The title compound was prepared according to the procedure described in Step 3 of EXAMPLE 2 using 4-isobutoxy-3-(piperidin-4-ylmethoxy)-1,2-benzisoxazole (EXAMPLE 10, Step 1) and methyl 2,2-dimethyl-3-oxopropanoate (0.96 mg, 0.74 mmol, Tetrahedron Asymmetry 2003, 14, 3371-3378) instead of 3-(piperidin-4-ylmethoxy)-4-(2,2,2-trifluoroethoxy)-1,2-benzisoxazole and methyl 1-formylcyclobutanecarboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816090B2
Source datasetuspto-grants-2014_08
ORD IDord-c8fe35b51dc44c169d9c8147793e397e
Source noteuspto-grants-2014_08