HCID 58437037, compound → HCID 58437038, compound

HRID 2410397Notes

Reaction equation

HRID 2410397 reaction equation
[C:1]([C@H:5]1[O:9][C:8](=[O:10])[C@:7]([C:18]2[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[CH:19]=2)([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[O:6]1)([CH3:4])([CH3:3])[CH3:2].C([C@@H]1OC(=O)[C@@H](C2C=CC=C(Cl)C=2)O1)(C)(C)C>>[C:1]([C@@H:5]1[O:9][C:8](=[O:10])[C@@:7]([C:18]2[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[CH:19]=2)([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[O:6]1)([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 58437037HCID 58437037, compoundHCID 67393109HCID 67393109, compound

Product 1

HCID 58437038HCID 58437038, compound

Procedure

Prepared in the same manner as (2R,5R)-2-(tert-Butyl)-5-(3-chlorophenyl)-5-heptyl-1,3-dioxolan-4-one using (2S,5R)-2-(tert-Butyl)-5-(3-chlorophenyl)-1,3-dioxolan-4-one. 1H NMR (400 MHz, CDCl3, δ): 0.84 (t, J=7 Hz, 3H), 0.96 (s, 9H), 1.16-1.35 (m, 10H), 1.88-2.06 (m, 2H), 5.35 (s, 1H), 7.26-7.30 (m, 2H), 7.50-7.54 (m, 1H), 7.62-7.63 (m, 1H). 13C NMR (100 MHz, CDCl3, δ): 14.3, 22.8, 23.7, 23.8, 29.2, 29.5, 31.9, 35.2, 38.9, 82.3, 109.1, 123.4, 125.4, 128.3, 129.7, 134.5, 140.5, 173.5.

Sources & evidence

ORD record
ord-4edb6283cd1f40a0bb028eab6060923c
Source dataset
uspto-grants-2014_08
Patent number
US08816095B2

Reaction notes

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