2-(Methoxymethyl)-2'-methylbiphenyl-4-carboxylic acid → (3-{5-[2-(Methoxymethyl)-2'-methylbiphenyl-4-yl]-1,2,4-oxadiazol-3-yl}phenyl)methanol

Participants

Role	Name	HCID	Charge
Reactant	2-(Methoxymethyl)-2'-methylbiphenyl-4-carboxylic acid	HCID 59495822	—
Reactant	N'-hydroxy-3-(hydroxymethyl)benzimidamide	HCID 74865044	—
Product	(3-{5-[2-(Methoxymethyl)-2'-methylbiphenyl-4-yl]-1,2,4-oxadiazol-3-yl}phenyl)methanol	HCID 59495704	—

Reaction Steps

The title compound was prepared following the general procedure 3 starting from Intermediate 3 and Intermediate 70 and was isolated as a yellow oil. HPLC (Method A) Rt 5.16 min (Purity: 97.0%).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08815919B2
Source dataset	uspto-grants-2014_08
ORD ID	ord-2a733703ea6b4180b55427e33933af88
Source note	uspto-grants-2014_08