4-Heptanamine → HCID 49854110, compound

HRID 2410613Notes

Reaction equation

C(OC(=O)C=O)C.CCCC(N)CCC.[O:16]1[C:20]2[CH:21]=[CH:22][C:23]([C:25](=[O:36])[C:26]([NH:28][CH:29]([CH2:33][CH2:34][CH3:35])[CH2:30][CH2:31][CH3:32])=[O:27])=[CH:24][C:19]=2[O:18][CH2:17]1>>[CH3:32][CH2:31][CH2:30][CH:29]([NH:28][C:26](=[O:27])[C:25]([C:23]1[CH:22]=[CH:21][C:20]([OH:16])=[C:19]([O:18][CH3:17])[CH:24]=1)=[O:36])[CH2:33][CH2:34][CH3:35]

Participants

Reactant 3

HCID 386654-Heptanamine

HCID 70211Ethyl oxoacetate

HCID 49854109HCID 49854109, compound

Product 1

HCID 49854110HCID 49854110, compoundYield 34%

Procedure

N-(heptan-4-yl)-2-(4-hydroxy-3-methoxyphenyl)-2-oxoacetamide was prepared from 4-hydroxy-3-methoxy-phenyl)-oxo-acetic acid ethyl ester and 4-heptylamine by the same procedure described for the preparation of 2-(benzo[d][1,3]dioxol-5-yl)-N-(heptan-4-yl)-2-oxoacetamide. White crystals of the title compound (0.7 g, 34% yield) were obtained.

Sources & evidence

ORD record: ord-87ca0db0f7314c8394833773d4af7cab
Source dataset: uspto-grants-2014_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08816102B2

Reaction notes

Loading…