3-Methyl-3-buten-1-ol → HCID 131731807, compound

Participants

Reaction Steps

An example of the method for synthesizing Compound (1) includes a method described below in Production Examples 1 and 2. In such a method, first, isoprenol is reacted with methanesulfonyl chloride in the presence of a base such as triethylamine to obtain methanesulfonic acid isoprenyl ester. Next, if needed, the obtained product is isolated and purified by a conventional method, and the obtained methanesulfonic acid isoprenyl ester is reacted with a malonic acid dialkyl ester in the presence of a base such as sodium ethoxide. As needed, a neutralization step is carried out using an acid to obtain Compound (1).

Provenance & Evidence