HRID2410921

反应详情

EQUATION

反应方程式

HRID 2410921 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

2

CONDITIONS

反应条件

温度
105 °C

PROCEDURE

实验过程

3-Bromo-7-iodo-9H-carbazole-1-carboxamide 481A (100 mg, 0.241 mmol), 4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)morpholine (84 mg, 0.289 mmol), PdCl2(dppf)-CH2Cl2 adduct (39.4 mg, 0.048 mmol), and Na2CO3 (2M) (0.602 mL, 1.205 mmol) were mixed with DME (4 mL) in a sealed microwave vial. The mixture was flushed with N2 and heated at 105° C. in an oil bath for 5 hrs. The mixture was used as it is. MS (ESI) m/z 450.97 (M+H)+.

WORKUP

后处理

  1. customThe mixture was flushed with N2