HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloropropanesulphonyl chloride → 4-(1,1-Dioxo-1lambda6-isothiazolidin-2-yl)-2-fluorobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloropropanesulphonyl chloride | HCID 15410 | — |
| Reactant | Methyl 4-amino-2-fluorobenzoate | HCID 21957875 | — |
| Product | 4-(1,1-Dioxo-1lambda6-isothiazolidin-2-yl)-2-fluorobenzoic acid | HCID 71252861 | — |
Reaction Steps
Using methyl 4-amino-2-fluorobenzoate (1.02 g) and 3-chloropropane-1-sulfonyl chloride (0.97 mL) and by the reaction and treatment in the same manner as in Preparation Example 16, the title compound (1.09 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-873014ac9eff437f97dc5758132085ad |
| Source note | uspto-grants-2014_08 |